WebApr 12, 2024 · Background: Tocotrienol, a type of vitamin E, is well known for its anti-cancer and other biological activities. This systematic review aims to summarize the involvement of endoplasmic reticulum stress (ERS) and subsequent unfolded protein response (UPR) as the underlying molecular mechanisms for the anticancer properties of tocotrienol. … WebTo test the hypothesis that overexpression of early growth response factor-1 (Egr-1) contributes to the revascularization of ischemic limbs, a constitutively active form of Egr-1 (Egr-1*) was made and evaluated in vitro and in vivo. Analyses of the transduced myocytes revealed significant upregulation of bFGF, PDGF-A, PDGF-B, IGF-II, and TGF-β1. A …
Early Growth Response Factor 2 - an overview
WebMar 30, 2024 · RAF proteins phosphorylate and activate MEK1/2, which further phosphorylates and activates ERK1/2 . The growth factor receptor bound-2 (Grb2) protein acts as an adaptor protein between the epithelial growth factor receptor (EGFR) and the guanine-nucleotide exchange (GNE) factor, son of sevenless (Sos) protein. WebJul 7, 2024 · We analyzed whole transcriptome expression to elucidate the potential role and underlying mechanism of action of lipocalin-2 (LCN2) in OPC differentiation and WMI and identified the receptor SCL22A17 and downstream transcription factor early growth response protein 1 (EGR1) as the key signals contributing to LCN2-mediated … how big is just cause 3
KLF10 Gene - GeneCards KLF10 Protein KLF10 Antibody
WebApr 4, 2024 · E3 SUMO-protein ligase EGR2, E3 SUMO-protein transferase ERG2, KROX-20, Drosophila, homolog (early growth response-2), early growth response protein 2, zinc finger protein Krox-20. GeneRIFs: Gene References Into Functions. EGR2-related mixed demyelinating and axonal Charcot-Marie-Tooth disease: An electrodiagnostic, … WebMay 2, 2024 · Figure 4 Renal early growth response factor-2 (EGR2) expression in wild-type and transforming growth factor-beta1 (TGF-β 1) transgenic mouse strains. At 14 days of age, EGR2 increased markedly in only CBAxB6-TGFβ kidneys, at both the ( a ) mRNA and ( b ) protein levels. WebAug 1, 2024 · The EGR2 gene, a member of the early growth response gene family, encodes a transcription factor that is a prime regulator of Schwann cell myelination. It … how big is kd feet