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WitrynaHuman NIS is an integral membrane protein that is involved in active uptake of iodide ions inside the thyroid cells, which has a crucial function in delivering iodine content required for the synthesis of thyroid hormones T3 and T4. ... the use of 2-DG and metformin has been reported as radiosensitizer, 19,20,28 whereas the use of both in ... Witryna7 gru 2024 · The pathogenesis of thyroid-associated ophthalmopathy (TAO) is still unclear, and therapeutic drugs have great limitations. As metformin has multiple therapeutic effects in many autoimmune diseases, we explored the effects of metformin on TAO in an in vitro fibroblast model. We used orbital connective tissues and … Witryna1 lip 2006 · The prevalence of thyroid disease in diabetes has been estimated at 10.8%, 2 with the majority of cases occurring as hypothyroidism (∼ 30%) and subclinical hypothyroidism (∼50%). 2 Hyperthyroidism accounts for 12%, and postpartum thyroiditis accounts for 11%. 2 Of the female patients with type 1 diabetes, 30% have … évorial