Pheochromocytoma pc12 cells
WebDec 28, 2024 · We have identified FA as a molecule that inhibits apoptosis induced by hydrogen peroxide (H 2 O 2) or actinomycin D (ActD) in rat pheochromocytoma, PC12 cell. We also found that FA reduces H 2 O 2 -induced reactive oxygen species (ROS) production in PC12 cell, thereby acting as an anti-oxidant. Then, we analyzed FA-mediated signaling … WebThe PC12 clone, developed from a pheochromocytoma tumor of the rat adrenal medulla, has become a premiere model for the study of neuronal differentiation.
Pheochromocytoma pc12 cells
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WebJan 6, 2015 · Vesicular exocytosis is ubiquitous, but it is difficult to detect within the cells’ communication mechanism. For this purpose, a 2 µm ultramicrodic carbon fiber electrode was fabricated in this work based on electrodeposition with over-oxidized polypyrrole nanoparticle (PPyox-CFE), which was applied successfully for real-time monitoring of … WebApr 13, 2024 · Pheochromocytoma 12 (PC12) cells derived from rat adrenal glands were purchased from ATCC (Manassas, VA, USA) and used for the experiments. PC12 cells were cultured in Dulbecco’s modified Eagle medium (DMEM), supplemented with 10% fetal bovine serum (FBS) and 1% penicillin–streptomycin at 37 °C in a 5% CO 2 incubator. The medium …
WebPC12 cells are a type of rat adrenal gland cell line that is commonly used as a model system for studying neuronal differentiation and function. PC12 cells were first isolated in 1976 from a pheochromocytoma, which is a rare type of tumor that arises from the chromaffin cells of the adrenal gland. WebPheochromocytoma PC12 cells were obtained from the Bioresources Collection and Research Center (BCRC-60048; Hsinchu, Taiwan) and maintained in the RPMI-1640 medium supplemented with 10% heat-inactivated horse serum and 5% FBS. All the protocols were approved by the National Cheng-Kung University Investigation Committee.
WebMay 1, 2007 · In rat pheochromocytoma (PC-12) cells the dopamine D 2 receptor agonists apomorphine (APO) and n-propylnorapomorphine (NPA) produced a concentration … WebMar 18, 2024 · This study aimed to determine the effects of reperfusion in an in vitro ischaemic stroke model—oxygen and glucose deprivation (OGD) (0.3% O2)—with rat pheochromocytoma (PC12) cells and cortical neurons. In PC12 cells, OGD resulted in a time-dependent increase in cytotoxicity and apoptosis, and reduction in MTT activity from …
WebThe catecholamine-secreting PC12 cell line derived from a rat pheochromoytoma originating from chromaffin cells of the adrenal medulla has long been considered a suitable model system for studying neurosecretion and neuronal differentiation.
WebThe internalization and subsequent fate of the two populations of nerve growth factor (NGF) receptors on pheochromocytoma PC12 cells were explored either by identifying the … discord bot tao 使い方WebApr 14, 2024 · The PC12 pheochromocytoma cell line of neoplastic chromaffin cells was established from a rat adrenal tumour in 1976 1. Treatment of these cells with nerve … discord bot tag roleWebThe rat pheochromocytoma PC12 cell line can easily be manipulated to study neuronal differentiation and apoptosis. When cells are cultured with serum, addition of PACAP inhibits cell proliferation and induces neurite outgrowth. When cells are cultured in serum-free medium, PACAP promotes PC12 survival and neuritogenesis. ... discord bot that asks questionsThe PC12 cell line has been used to get more information about diseases of the brain. It has been used in research of hypoxia, where acute hypoxia induces exocytosis and prolonged hypoxia can induce excessive exocytosis. PC12 cells were used to find which prion protein fragments caused neuronal dysfunction. In … See more PC12 is a cell line derived from a pheochromocytoma of the rat adrenal medulla, that have an embryonic origin from the neural crest that has a mixture of neuroblastic cells and eosinophilic cells. See more This cell line was first cultured by Greene and Tischler in 1976. It was developed in parallel to the adrenal chromaffin cell model because of its extreme versatility for pharmacological manipulation, ease of culture, and the large amount of information on their … See more Research has shown differences in vesicle size and quantal size depending on treatment with certain drugs. • L-DOPA has shown increase in average quantal size when treated for only 40–90 minutes. • Treatment with amphetamine or reserpine causes … See more • Wikipedia articles containing the term "PC12 cells" [1] • Ras function was partially elucidated using PC12 cell line [2], from section in Cancer Medicine textbook See more Their embryological origin with neuroblastic cells means they can easily differentiate into neuron-like cells even though they are not considered adult neurons. Neuron-like means they share properties similar to neurons, in this case it is referring to releasing … See more PC12 cells have been researched to evaluate the potential for pharmaceutical alternation of dopamine metabolites such as DOPAL, an autotoxin implicated in the pathology of See more • Cell culture • Adrenal medulla • Cellular differentiation • Pheochromocytoma See more discord bot that acts like a personWebJan 31, 2024 · The PC 12 cells remained viable and physiologically healthy, as confirmed by a panel of biological assays; however, exposure to THz radiation for 10 min at 25.2 ± 0.4 … discord bot that assigns rolesWebFeb 21, 2024 · TNTs were first described in rat-cultured pheochromocytoma PC12 cells , and subsequent studies have shown that they connect a wide variety of cell types. These studies provide more evidence that TNTs are involved in mitochondrial transport between cells, the repair of cell damage, the activation of enhanced immune responses, and cell … discord bot that auto deletes chatsWebAug 5, 2024 · In rat pheochromocytoma PC12 cells, Wnt3a treatment enhanced cell proliferation and suppressed mRNA expression of tyrosine hydroxylase (TH), the rate-limiting enzyme of catecholamine biosynthesis, and dopamine secretion. We identified the expression of sclerostin in PC12 cells, which is known as an osteocyte-derived negative … four corners marina nashville